I'd add one thing to BudFox's list, that helps me a great deal with the "waking up at 4am" problem: I take phosphatidylserine, which is just a form of an amino acid. It's sold under the brand name Seriphos but I just take a generic kind, 500mg the evening before. Works wonders for me and is a godsend, but everyone is different. I can only take it 3-5 evenings in a row before I start finding it a little harder to get up in the morning, so I only take it when needed. Hope you start finding some relief soon Maria, at least in some small ways.