I had the same thing with seroquel. I only had a half hour commute but I had to leave at 7am and it wasn't enough time for me to sleep off the sedation from the seroquel. I would struggle to keep my eyes open while driving. It was really scary and really dangerous. I chose to go off seroquel completely after just one month, even though it pulled me out of a severe depression. I would get off of it asap. See if you can find another med for depression. You're playing with your own life, as well as the lives of others. No medication is worth your life, no matter how well it works. I hope you find a solution soon.