I have a hard time taking birth control hormones because they make me really depressed, and sometimes manic. Very volatile and emotional. They are powerful stuff. I prefer my body's natural hormones to taking artificial replacements, but I am now at the stage I need artificials to suppress my ovulation due to ovarian cysts. It's a can't win situation. Beware of hormones! I am in perimenopause but can't say I feel any more depressed than before that, except for the articials I just started taking recently.