Quote:
Originally Posted by justanotherone97
hello everyone, i just wanted to ask which drugs increase the serotonin effect in the brain? and which drugs combined increase the effect of serotonin? I know that ssri works on serotonin but i've also red that maoi's combined with ssri's can actually work better than if you only take one ssri. finally do you know which combination of drugs are better for treatment resistant depression? i have tried many antidepressants combined with citalopram but no one works...
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Sorry you feel your SSRI isn't helping.
Sometimes when necessary a psychiatrist may cautiously combine more than one antidepressant but there are serious risks of toxicity if not managed carefully by a specialist.
The most serious is serotonin syndrome which can lead to shock, convulsions and even death. This link might be helpful, but remember to cross check anything you read on line.
https://en.m.wikipedia.org/wiki/Serotonin_syndrome
My Pdoc point blank refused to make certain combinations due to the risk of serotonin syndrome - he didn't want to poison me.
Best wishes as you try to find a way forward.
