Hey. I haven't had experience with it, but have heard that sometimes medications can have 'paradoxical effects'. Some people find that Prozac makes them feel 'better than well' and some other people find that they experience agitation / anxiety (that is DIFFERENT from the kind of agitation / anxiety found in unmedicated depression) and are sometimes led to harm themself and / or to harm others. Sounds like that was what was happening with her on the Prozac. That can be very dangerous (people have attempted suicide and / or harmed others when experiencing that kind of a response to Prozac). I'm glad that she was monitored carefully and that the p-doc stopped the Prozac when she experienced those side-effects.

It might be... That if you have a paradoxical effect from one medication (e.g., Prozac) that you are more likely to have paradoxical effects from other medications. I'm not sure that paradoxical effects have been studied that much (people prefer to study benefits rather than harms).

> She's been on it two days and already having nightmares, thinking there were strangers in the house, woke me up last night to see if someone rang the doorbell and if i had been up

Is she usually like this or are you noticing a distinct change? Can you ask her how she feels? Agitated? Like she has to move around / jiggle? Feeling a bit paranoid? If this is a change for her... I'd phone (or get her to phone) her p-doc and make an appointment ASAP. I'd make sure they know about her response to Prozac such that they seriously consider that this could be a medication induced change.