Darlene:

I looked it up on my account with Walgreens.com and they have it listed as these two meds having NO interactions whatsoever. This was the highest dose form of Glucosamine Chontroitin and 20 mg. Lexapro. So, perhaps it's just time to up the GC. I know my husband was on it for awhile and it seemed after a certain amount of time it took a higher dose of GC to have the same effects as in the beginning.

Good luck!
Kimberly.