That's intense. I can't do seroquel, so I take Abilify. I take 2 anti-epileptics, but mine aren't too sedating (Trileptal and low dose Lamictal). Even then, I need relatively high dose (400mgs) Wellbutrin to function.

If you're manic and psychotic, though, I would think your tolerance for sedatives would be higher (?). I mean, makes sense, intuitively. I hope you can work with your doctor to taper off some of the sedatives over time, as you calm down and reach the magical state of full on lucidity.

Do you plan on taking two major tranquilizers long term? Have you had any muscle stiffness, tremor, tics, etc.? I knew somebody on Navane and a new tranquilizer (maybe Saphris?) once, and she said the combination was fairly tolerable.

Hope everything works out for you.