Zyprexa didn't work for me either. No response at all.

Seroquel dosing is approved up to 800 mg. I was up to 1500 mg at one time so you can go WAY up if your pdoc does that (it was special circumstances; I was pretty much out of meds to try that weren't likely to give me a bad, rare reaction I've struggled with on various APs). So you have room to go up.

I've been on over 40 med and 71 combinations in the last 14 years. I am finally fairly stable on clozaril. In fact aside from stress from my family I'm doing well. But I know how hard it is to wait and wait for the right combination.

Sometimes the older APs are the ones that work. I was on loxapine (with Seroquel) last year for a while and while I had my rare reaction and had to stop it it really helped. Or the 2 meds together helped I guess but I don't think seroquel was doing much at all by then.

Do you know when you see a pdoc again? are you scheduled with someone else at the place you've been going (I think ethically they would have to do that).