Hi bpenniman! I was on Latuda for about 4 months on doses from 40 - 120mg a day. To be honest I did not notice any improvement in my depressed or mixed states. A month after the mixed state ended I fell into a deep depression and it did not help at al. And yes, I had much lower libido. On the plus side I actually began to lose weight, mostly because i was no longer taking Olanzapine at that point. Back on it temporarily now but will get off the olanzapine asap.

So sorry, no good news hear but everone is different and i have heard great reports. Good Luck