I'm on Sertraline. I'm also on anti-biotics but that's for my scalp condition. xD (although it's affected me because of the side effects x_x)

I'm on the 2nd week now, and as such, my dose went up twofold. So far so good. I find it starts wearing off in the evening and especially the morning, but soon gets back into gear once I've taken sertraline again. I do notice an improvement regarding my anxiety, and because the anxiety is less, there's a less chance I get swept away by my crazy brain thoughts. I see my doctor again after the 3rd week is up. I imagine he'll either put me up a dose again, or just suggest I stick with what I have so I'll have a repeat prescription.