Kimber, I've had those programs you mentioned but not too long ago, my puter got infected with the Swizzor trojan. NONE of the programs I have, including McAfee were able to fix it so I went looking. I found the program "A Squared" that finally got rid of it. Spyware Doctor left a .dll file in my puter that not even A Squared can get rid of. I've done a search for the file, but it's really hidden! Even used the "add/remove" option to remove Spyware Doctor and when I deleted it from my puter, it told me that there was one file that had been left. Ad-Aware doesn't find it because it and SD are from the same company. A Squared calls it "critical."

Oh! And A Squared has a help forum, too! I like that! Questions get answered the same day. At least, mine did.

I hear "Hijack This!" is a great program, too, though.