Thanks for the replies. I see my shrink on Tuesday and will talk about my disorders etc and current med status. I don't think I will be going back to the citaloprams unless it is with some adjunct agent as I have quit coffee and nicotine (over a year ago) due to a headache disorder and now the citaloprams both make me tired and want to sleep all day. Coffee also caused me anxiety. This is one of the reasons I wanted to try Zoloft too cus I hear it is more activating and could take care of the anxiety and depression. Anyway, I was told that I probably want to get up to a target Zoloft dose of 100 mg/day. I am currently on Day 12 at 50 mg/day and experiencing insomnia, the jitters, anxiety, lack of appetite. I think I need to push on as I hear a lot of anecdotes about things getting worse before better. I hope that is the case for me! I have clonazepam (0.25 mg tabs) for as needed during this transition, but am worried about using too much of it. I can't even remember what it was like a decade ago when I first started SSRIs... It seems that I am too neurotic about everything currently and need to trust in the process and my doctors.