Adderall is not labeled for use as a primary treatment for depression, but it does produce effects that are beneficial to sufferers. Amphetamines like Adderall modify production, transmission, and reception of norepinephrine in certain parts of the brain, which helps to promote energy and alertness. Since some of the key symptoms of depression are a profound lack of energy, motivation, and torpid states that are the antithesis of “alertness,” this indication does make sense. Particularly when depression is characterized by profound despondency, the use of Adderall as an adjunct to an antidepressant can help to restore vigor and attentiveness.

Adderall is an addictive prescription stimulant with effects similar to cocaine. People regularly taking Adderall at unprescribed doses are at a high risk of becoming addicted.

It works by increasing dopamine levels in the brain. Dopamine, the body’s “feel good” chemical, creates a rewarding effect. Although dopamine occurs naturally, drugs like Adderall produce unnaturally high levels of it. This can cause users to come back for more.