I am currently on 300 mg. Actually, I was on 400, then a pdoc dropped it to 300 mg a while ago since she said there is no research as far as she knows, that there is any benefit past that amount (that's not to say that maybe a small group of people notice a little bit of a benefit). Plus, side effects go up after 300 mg. Personally, I never noticed a difference between 300 mg or 400 mg as far as mood stabilization. So I think I can pretty much conclude that Lamictal isn't doing much to help me at this point. Maybe an add-on mood stablizer to enhance the Lamictal could help, along with my AP and benzo, but I'm just surmising.