A few months ago I got the bright idea to take Wellbutrin without an AP or stabalizer. I wasn't exactly trying to trip hypo but more desperate for the depression to go away which it did and Hypo came along for the ride and I immediately called my doctor, stopped the Wellbutrin and started an AP. Now I'm just waiting to adjust to the AP so we can add a small dose of Wellbutrin and I'm really confident the combo will be life changing in a positive way for me. Before I knew about triggering hypo I did it unintentionally all the time. Hypo is a good feeling and since I'm usually dangerously depressed, it's also safer than depression....but it can lead to mania and that is just a wild card I can't trust or count on. ((((Hugs to you blue))). Be safe.