Yes, cured it with just tryptophan.
I tried 5htp before this and didn't do anything for me either.
How are you going with the niacin? I'd get the one that gives you a flush
I tried that before tryptophan as well as melatonin. Because they both worked well for me, I switched to tryptophan, as the body makes those things out of it. It's like the base ingredient.

Good to know about the B6.
I've tried GABA in the past which helped with anxiety.
I've started taking a essential amino mix recently, and I've been on a natural multivitamin for a long time, but I don't feel like they actually cured the depression.

This site helped me get onto it: Dominate Depression | Overcome Depression For Good Maybe you've seen it?

p.s. I first tried melatonin, which helped my sleep. I then tried niacin, which gave me a part of my energy back. But it was not until I started taking tryptophan, that both of those things improved, as well as my mood; I feel happier, I feel like I can do things again, I've started thinking about the future again, getting creative. It's like I'm starting to feel my emotions again or something. Got a part my motivation and energy back.
Pretty neat

This is compared to me having insomnia, no energy, no motivation, no thoughts about the future, simple things like cooking drained me, numbed emotions, no hope, etc.

And when I say cured, I do mean that I still take this supplement. I feel like I'm a huge part of the way back to normal, no longer depressed, and I keep seeing improvement over time. My family say I've improved tremendously too.