I've been trying different meds for some time, and throughout the years I've tried different vitamins and supplements here and there. I take vitamin d, which I think probably helps some, and fish oil semi-regularly. I'd been considering trying to just go with less meds (only on lamictal now) but keep remembering how bad my depression and anxiety are and why I need meds in the first place.

I'm pretty desperate for relief and planning on asking my pdoc for EMSAM at my next visit. I'm having second thoughts though, because I'd recently been researching more supps and planning to try them, but I know I can't really do that much if I'm starting EMSAM (difficulty telling what's helping what as well as possible interactions). At the same time, again, I'm badly in need of relief from my depression right now.

Most recently I tried rhodiola rosea, and while it wasn't for long so I might eventually give it another try, I was pretty sure it was making me feel odd, out of it, and kinda crappy so I quit it. I tried chromium picolinate a while back, only for a few days but it was similar. I'm pretty interested in trying NAC next.

When I've heard people say they take only supps and natural stuff for depression and anxiety, or say they're "cured" by them, I brush it off as them being someone with much less severe anxiety/depression.

Is there anyone who has severe anxiety and depression and has actually found the right supplements/natural things to really help them enough? I'm talking like, people who have needed meds to even function well, but now are able to do without largely because of help from supplements. I'm not expecting a simple supplement to cure me, obviously, but would it be reasonable enough to try to make it with that route, or should I focus on meds and use supplements more as a small boost?
Thanks!