My wife constantly reminds me that I don't "let go" on vacation and the more anxious and depressed I feel, the more regularly I'm checking work emails and ruminating about work. I try and keep busy during the day--exercise, be with other people, do anything to distract myself. Early morning is the worst for me, even on vacation. Thank goodness for BBC World Service in the early hours, which I listen to to 'escape' from my whirring, negative thoughts. Can't say I've had a "fun" and relaxing vacation for a while.

I hope your situation improves.