Hey all. Been on 100 mg Zoloft for just over two weeks now. I titrated up pretty quickly to 100 mg after quitting Lexapro (6 weeks ago) and have been really depressed and anxious lately. I feel like my depression has been getting worse since starting Zoloft and my anxiety is worse for sure too. For about a week now, I have been experiencing side effects of Zoloft that I especially experience a couple hours after taking Zoloft. It is giving me a dull headache (all over but seems to radiate up from my neck), bad fogginess, nausea and agitation. Can't really seem to kill this pain as I can't really use pain meds (I get rebound headaches). Anyway, just wondering how long one needs to stick out these side effects. Trying hard to push through and give this med a chance, but I feel like it is making me sick. I am going to try to call my doctor tomorrow regardless. I am pretty neurotic about things right now and have lost a lot of confidence or hope in this treatment.