Right now I'm at 100mg and haven't noticed a huge difference because I am still feeling depressed, albeit better than I was a month or so ago. When I last saw my pdoc right before Christmas he put me at the 100mg and I believe the plan is to titrate me up slowly. One thing to watch for is the rash that can come with taking Lamictal and I think that's why my pdoc is taking a little slower than some others might.