A couple of years ago, I smoked some weed during a severe depressive episode. Two days later I was in the hospital watching black and grey cats running underneath the linen cart; all my previous occurrences had happened during mania. Did the MJ cause the psychosis? Who knows? But I've been very careful ever since...I will only smoke when I'm not in any kind of episode, and even then I smoke only when my oldest daughter and son-in-law come for a visit. I've never bought any for my own use, I just bought it for my husband when he was still here and needed help with his cancer pain and nausea. Who knows, maybe I'll buy an eighth one of these days.