zyprexa and depakote both packed on the pounds for me. I'm going of zyprexa (left depakote years ago) gradually now. I can't stand being this fat. I started a diet 2 weeks ago and although I think I've lost a bit of weight (by the way my clothes fit), I can't really tell on the scale. The scale says things within a 5 pound range, so I guess I'll have to get on first thing in the morning naked or something once a week.