A quadriplegic could very well be incurable. Or blindness. All sorts of things. Do you think they feel "why bother staying alive"? There are lots of things in this world that are incurable, including AvPD.

Meds don't work on AvPD if that's all you have. Why? Because they work when there is a brain chemical imbalance. AvPD is a personality disorder, not a brain chemical imbalance. You can also have another condition, but if it's just AvPD, medication won't touch it.

And actually you have proven my original point. AvPD is not about isolation. You can be a social butterfly. But you don't feel worthy of it, and you don't make deep connections with people.