I have fibromyalgia, scoliosis, sciatica, and inflammatory arthritis. I take nabumetone (or Relafen) 2x/day and tramadol PRN up to 2x/day. I also take Plaquenil every day, which makes me a crying mess sometimes, but seems to work better than nothing.

It took me a long time to get to a right mix of meds w/my doctor. I worked through several tiers of NSAIDs before I finally asked her if I could try tramadol for the really bad days. I don't take it all the time, but it does help on the really bad days where I'm hurting so much I can't think about anything else.