I used to take 2 Benadryl, 10mg melatonin and 2 ambien and sleep. Then the new doc cut the ambien in half and I slept from midnight to five. But he's not refilled the script in two weeks. I still take the Benadryl and melatonin but my body just laughs. I've had trouble sleeping my whole life except for a few years when I was a teenager. I've taken as much as 5 Benadryl but not sure how much more than that I can take safely. Not sure about the melatonin either.