I've put on almost 20kgs since June-July & I noticed that was when I had an increase in seroquel & added Valproate. I managed to lose 4 or so KGs hen I was last in hospital but I put it back on not long after coming out, plus another 3kgs... I haven't exactly tried to lose the weight even though I really want to. I guess I need to commit myself to losing it before I can say whether it's going to be hard to lose