I was on olanzapine for three years then I switched to the Seroquel extended release and it was more effective on my mood. I would just say you have to stick with it for a while, i.e. try and get used to the sedation (within reason of course) so time off work may be needed.
when I was sectioned for suicidal ideation, the doc took me off Seroquel to try a different drug. I tried abilify on its own and it didn't work for me, risperidone didn't either, and chlozopine nearly put me six feet under.
Eventually I was put back on quetiapine yay! But I still need more for my mood than it alone. I think it works best on my mania and concentration.