Loxitane has a weird property that it partially metabolizes into an antidepressant (amoxapine) on the way out. So it should help anxiety/depression a little more than other APs by that action.

I was on it for several months about 2 years ago. It helped my depression somewhat but I had some dangerous side effects and had to come off it before we got the dosage high enough. (Don't worry about it, it was rare and I'm very sensitive to meds. It is extremely unlikely you'll have problems like I did). I actually liked it. I lost some weight and it had few side effects until the problematic one kicked in. It wasn't even that sedating but helped with sleep which is a major problem for me.