I have been taking clozapine for bipolar for ten years and it works well for me. It has a fairly short half-life though so if I don't get my refill I tend to get hypomanic after missing two or three doses.

Currently the clozaril registry requires a CBC once a week for six months, every two weeks for six months and every month thereafter. Neutropenia is rare but dangerous but I have always had good labwork so for me the drug is a good choice.