I think I started to talk to my son about it when he was 6. He has ADHD though and potentially a mood disorder, so I think it helps make him feel less "weird" that mom took meds too. We got our diagnosis the same month. I have always wanted him to understand that just like how he acts in ways he cannot control, so do I. Don't want him to think it's his fault if I suddenly become irritable or withdrawn.
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