Well depression is definitely a problem which you need help with. Talk to your mental healthcare providers.

There are issues deeper than this - I believe the depression is a symptom of a bigger problem.

You mention an inability to connect with people and make acquaintanceships. Have you given consideration why? What do you observe is different about your attempts to do so an others who are more successful. If you haven't paid this attention before, perhaps you should. Observe how others behave and communicate around others. In particular watch the non-verbal communication. This actually means more in social interaction than what is said itself. What sorts of things said or actions do people most respond to and what do you notice turns them away? Would it be fair to say you owe yourself some self reflection?

If you want social interaction you need to take responsibility for it happening. It isn't going to happen by itself.

Unfortunately it doesn't come easily to everyone. Sometimes it must be a learned behaviour.

It is important that you discuss this with your psychiatrist too.