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Old Mar 14, 2017, 04:15 AM
TicTacGo TicTacGo is offline
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Member Since: Dec 2016
Location: South Africa
Posts: 446
Benzodiazepines- a summary by TicTacGo (sources below)

Long acting:
-chlordiazepoxide (Librium)
• Onset: intermediate (PO)
• Peak: 2-4 hours
• Half-life: 5-30 hours
• Oral equivalent: 10 mg
• Indication: anxiety
-diazepam (Valium)
• Onset: Rapid (PO/IV)
• Peak: 1 hour (PO)
• Half-life: 20-100 hours
• Oral equivalent: 1 mg
• Indication: anxiolytic
-flurazepam (Dalmane)
• Onset: Rapid
• Peak: 0.5-2 hours
• Half-life: 40-250 hours
• Oral equivalent: 30 mg
• Indication: hypnotic

Intermediate acting:
-alprazolam (Xanax)
• Onset: intermediate
• Peak: 0.7-16 hours
• Half-life: 6-12 hours
• Oral equivalent: 0.5 mg
• Indication: anxiolytic
-clonazepam (Klonopin/Rivotril)
• Onset: intermediate (PO)
• Peak: 1-4 hours
• Half-life: 18-50 hours
• Oral equivalent: 0.5 mg
• Indication: anxiolytic, anticonvulsant
-flunitrazepam (Rohypnol)
• Onset: intermediate
• Peak: within 2 hours
• Half-life: 18-26 hours
• Oral equivalent: 1 mg
• Indication: hypnotic
-lorazepam (Ativan)
• Onset: intermediate (PO)/rapid (SL and IV)
• Peak: 1-1.5 hours
• Half-life: 10-20 hours
• Oral equivalent: 1 mg
• Indication: anxiolytic
-oxazepam (Serax)
• Onset: slow
• Peak: 2-3 hours
• Half-life: 4-15 hours
• Oral equivalent: 20 mg
• Indication: anxiolytic
-temazepam (Restoril)
• Onset: slow
• Peak: 0.75-1.5 hours
• Half-life: 8-22 hours
• Oral equivalent: 20 mg
• Indication: hypnotic

Short acting:
-midazolam (Versed)
• Onset: rapid (IV)
• Peak: 0.5-1 hour
• Half-life: 1.4 hours
• Oral equivalent: / (used as IV)
• Indication: hypnotic
-triazolam (Halcion)
• Onset: intermediate
• Peak: 0.75-2 hours
• Half-life: 2 hours
• Oral equivalent: 0.25 mg
• Indication: hypnotic

-Similar acting non-benzos
-zaleplon (Sonata)
• Onset: rapid
• Peak: 1 hour
• Half-life: 2 hours
• Oral equivalent: 20 mg
• Indication: hypnotic
-zolpidem (Ambien)
• Onset: rapid
• Peak: 1 hour
• Half-life: 2 hours
• Oral equivalent: 20 mg
• Indication: hypnotic
-zopiclone (Zimovane)
• Onset: rapid
• Peak: 1.5-2 hours
• Half-life: 5-6 hours
• Oral equivalent: 15 mg
• Indication: hypnotic
-eszopiclone (Lunesta)
• Onset: rapid
• Peak: 1 hour
• Half-life: 6 hours
• Oral equivalent: 15 mg
• Indication: hypnotic

Source: benzo.org.uk : Benzodiazepine Equivalence Table
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Tic-Tac
Thanks for this!
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