I have been on meds 40+ years starting w thorazine and an maoi in 1970. Haven't had any long term side effects yet.. no I m not on those particular drugs now but have been through all of the old antipsychotics and the new ones throughout the years. I m a senior now. If it hasn't damaged me now I have no fear about the next 10 or 20 or so years. Again people are different in how they react to meds but just because you are on meds doesn't automatically mean that eventually you will be damaged by them. Sometimes after a long time you may develop a side effect and then the meds need changed. But you learn your bodies signals and you work closely with your pdoc if you have unreasonable side effects until you get on a combo that works or works again. Yes some people can be adversely affected but that isn't a 100 percent given for every person.