Neither Seroquel nor Latuda did anything for hypomania for me. Seroquel works great for my anxiety and OCD stuff. Latuda made my skin crawl and just generally made me feel weird. I was only on it for a week and my doc took me off of it.

I'm on Vraylar now and loving it. It's weight neutral and seems to work well for both depression and hypomania. It's not a quick fix, though. Seemed to take several months for effects to really kick in.