hi. I'm from the US, so the brand names weren't familiar to me. I look it up, and she's been prescribed clozapine, risperidone, and an anti-cholinergic drug.

clozapine and risperidone are both "atypical" antipsychotics. Its kind of unusual to see clozapine with another tranquilizer, but it happens. What are her doses, do you know?

The Hexymer is for side effects, as best I can tell. With high enough doses of any tranquilizer--"atypical" or the older ones--people get muscle stiffness, tremor, etc., and anti-cholinergices decrease these reactions.

I'm not any kinda doctor, but risperidone can raise prolactin levels a lot, which can mess with hormones and cause all kinds of problems. The clozapine can be densely sedating, and now and then people have fatal reactions to it (in the US, they require extensive blood work for clozapine-treated people...). Seizures seem to be another very serious concern with ongoing clozapine treatment.

I don't have any advice for you ((sorry)), except maybe see about a different tranquilizer. here in the US, clozapine is for treatment-resistant Schizophrenia. Its effective, but it comes at a cost. Adding risperidone seems like it would complicate things a lot and maybe lead to more side effects, especially with the prolactin issue involved.

I hope your family+your sister's doctors can get this all straightened out. :-)