hi. Paxil is very potent on serotonin receptors. tapering is sometimes kinda rough ((not trying to scare you, just thought I'd mention it)). Bupropion is a more stimulating drug for depression, and it can help reduce some adverse effects from the SSRI drugs, such as Paxil.

Paxil is often used in anxiety, depression, and OCD. Bupropion is useful for some forms of depression. It can also help reduce some symptoms of ADD/ADHD.

What are you looking to improve? Phentermine is approved for use in weight reduction. I've taken it, and its OK. I personally found the more popular psychiatric stimulants (Ritalin, Adderall) to be better for my set of problems, at that time. For my weight loss, I was switched to Phendimetrazine (Bontril), and I found it easier to tolerate than phentermine, and also a good bit more effective.

Some psychiatrists are using modafanil and NuVigil in some cases of depression, fatigue, etc. I've never tried it, but it does help some people, and you can get refills on it (Adderall, Focalin, Ritalin, are Schedule II substances, so you need a new written prescription for every fill. Kind of a hassle if you're not close to your prescriber...).

High doses of wellbutrin are sometimes used to help curb appetite and help with weight management. I don't know how well that works. I was on 400mgs/wellbutrin. It lifted my mood a bit, but I dropped it because I felt a bit too on edge and nervous on the higher dose.

Mixing stimulants with SSRI, SNRI, and some TCA drugs increases the risk of serotonin syndrome. Serotonin syndrome is not very common, but the risk is not 0. Wellbutrin can make stimulants somewhat less effective, because it inhibits the reuptake of norepinephrine and (I think...) dopamine.

Anyway, the choose of drug(s) really depends on your problems. If you're fatigued and such, something stimulating might be a good idea. If its more anxiety, then maybe an SSRI, SNRI. If you're feeling apathetic, you might want to avoid SSRI, SNRI, and probably most TCA drugs.

I hope this helps.