I have heard that meds don't work the same after you've come off of it.
I've tried quite a few.
Celexa - at low dose it made me drowsy. At a higher dose I got screaming headaches.
Prozac - didn't work even at max dose
Effexor - wasn't working well enough even at max dose
Serzone - didn't really give it a shot to work.
Zoloft - the first time I was on it it caused mania. Now I'm back on it in conjunction with a mood stabilizer and I'm relatively happy with it. I think I need an increase.
Keep in mind everyone reacts differently to meds and there are plenty of people here that will have opposing views on meds.
I think I was on something else too but I can't remember.
I hope you find something that works well for you.