Soo sorry you are feeling this way,bluebicycle. It is hard when the pdoc is trying to adjust your "cocktail". I had tremendous issues with antidepressants 16-18yrs ago,back then i probably tried somrwhere between 10-15,all with horribke side egfects,wprse symptoms at times or mot helping...finally,my pdoc tried old school med-elavil. I say this to let you know,yes,sometimes you can get worse on antidepressants without something else to valance it...they gave me gabapentin-ahain-not usual as a mood stabilizer...but many other types od meds made me worse