I second what Jenna said. PCOS and high testosterone levels are highly correlated. It seems that when my testosterone levels are high, I also seem to be more depressed. Plus all of the other fun PCOS issues. I've never taken spironilactone, so no input there. I hope the medication you're on is helpful! If not, I'd consider talking to your doctor about possible PCOS. There are ways to treat it separate from dealing just with the testosterone