Hi there, I posted a couple times before but thought I'd share the outcome of my latest pdoc appt... after rattling off my list of meds I've tried and him declaring there weren't many options left, he suggested buprenorphine or suboxone.... it's technically an opiate, but it's like the methadone for opiate addicts, so it's supposedly not addictive and you don't really build a tolerance like most opiates. It works very quickly too, in hours! However you do have to titration up to the target dose, which my doc said was either 2 or 10 mg for his patients.

There's been a few studies on this but it's very new to be used for depression, the article of the study he gave me was from last month! I'd imagine not a lot of pdocs would try it, but mine is quite out-of-the-box and works most with trd patients so not unusual he'd be willing to try new things.

I've only been on it two days, and there's no overwhelming change yet, but I haven't been sad, either! I may just be having a few good days so too soon to tell, but so far so good!