Seroquel Is a funky drug 100mg and below it's a heavy duty anti histamine at much higher doses it has its antipsychotic effect , for sleep problems Seroquel is contraindicated just as all anti psychotics are the AASM released a paper about 1.5 years ago telling Physicians to stop treating insomnia that way because antipsychotic medications causes negative changes in the sleep cycle ( circadian rhythm) and sleep architecture, Doxepin is a failed antidepressant from many years ago that has been studied extensively in sleep labs and has positive effect on sleep it has been repatened as Silenor for sleep . Almost all psychotropic medication has an antihistanergic effect in its profile simply because all psychotropic are based off antihistamines. Get Your allergy test! Food allergies are very prevalent and annoying.