I've noticed that my depression has been getting worst before & during my menstruation. My psychiatrist said that I may have PMDD so she added Zoloft to my current meds, which was Effexor.

It was okay for a little while (maybe 2 months or so), but now it's getting worst again. She told me to increase my Zoloft from 1 to 2 pills daily. Every time my depression gets worst, she always increases my dosage. I'm worried.

Does anybody take something else that has been working for their PMDD?

I'm 39 years old & already had my tubes lasered. I heard about a hyrestictomy (sorry, I don't know how to spell it. . . but it's when they remove your womb through surgery). . . is that supposed to help as a last resort?