I have been on Seroquel for years. It has the opposite affect on me, I don't crave food. Sleep is wonderful. Sometimes I use it to lower my mood when I am creeping into hypomania. With 100 mg, I can drop my mood in 30 minutes, but I have to be careful of when I take it. For example, I don't drive while on it. So I'll take it at the end of the day when I don't have an activity that requires that I be attentive.