I think it is hard to get a precisely right dose of clozapine. I've been stable at 275 mg for 9 months or so and my pdoc says I can go down but I have to get through the spring and early summer first because I tend to go manic during those months. But every adjustment has been tiny and she's wanted me to stay on each dose for a while before any change.

I'm really sedated on it too (and hate the weight gain) and frustrated but I know that I've been through the other meds and they didn't work once and I'm not willing to try them again and then still need clozapine. But I do hope I can get to a dose that works without so much effect on my life.