Yes, back in the early days of being diagnosed, I took 900 mg of Seroquel, daily. That was back when they didn't know a lot about it. I can also remember a time when I took 50 mg and got the same effect.

Today, I use Seroquel to knock my mood down. Usually 200 mg. takes care of the immediate problem.

The key for me is that when my mood is elevated, I don't always know it, until a chain of events take place and it is pointed out to me. I live alone so sometimes I don't catch it and eventually wear myself out.

900mg used to be fairly common.