I take lamictal in the morning and at bedtime. My current pdoc wanted me to take it all in 1 dose but I prefer twice a day. I don't take it on an empty stomach but I am on a lot of other meds so I couldn't say which ones make me nauseous if I take it without eating anything.
Never got a rash.
I do wonder if my vision issues (I need reading glasses after always having perfect vision but it could just be I am getting old!) and sun sensitivity (I burn very easily) are connected with lamictal though.
My old pdoc who put me on it basicallly said drinking wasn't a good idea but wasn't really dangerous either. He didn't want to say that mixing it with alcohol would cause some awful reaction just to have me try it and be fine and then think of him as lying to me... but I am not a big drinker.