I am severley depressed especially in the mornings. i find it hard to get out of bed always plus i have degenerative disc desease which makes it hard to move my back to even get out of bed. Then it's coffee time my first cup of coffee gets in my system and i start to feel better. i don't know what i'd do without coffee, the caffeine in it keeps me going. i also have bipolar, schitzoaffective disorder, PTSD and was in 3 accidents. well i guess i have to live with it and hope a newer pill comes out for me and others. good luck to us all!!