I'm one of those who uses Metformin to manage my weight. I lost some while on it and now have managed to stay relatively the same for a year now. I didn't lose enough to put me back to my original pre-medication weight but the loss was significant - two clothing sizes. I've been able to maintain this.

There are some side effects. I'm not troubled badly but, how shall I say this?... um, er... people get the runs from Metformin.