I take 250mg of Pristiq and 800mg of Seroquel, and 3mg of Lunesta...

Even when I downsized the dose my nightmares were just as bad. I have seen no difference either way.

I also have Ativan to take if I am manic. My sister controls my taking of this because I abused it. I also have a stronger sedative that she administers if I need to calm down but none of this calms me down to prevent a nightmare...