Most "Tweakers" or meth users I know fell into staying up for 48 - 72 hours without sleep. The drug is so powerful that even after 3 days of no sleep, they usually need something to knock them out, (unless they run out and crash).. Its not uncommon for them to use Anti Psychotic med's or Heroin to get some sleep.

Its common to sleep 48 hours or more, wake up depressed and with strong cravings, and immediately go out and find more Meth.

Not all meth users are like that, but most end up that way .. Its progressive, it never slowly gets better.